HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxy-1-(2-methoxy-4-nitrophenyl)-1H-imidazole → 3-methoxy-4-(4-methoxy-1H-imidazol-1-yl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxy-1-(2-methoxy-4-nitrophenyl)-1H-imidazole | HCID 117824150 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-methoxy-4-(4-methoxy-1H-imidazol-1-yl)aniline | HCID 117823841 | — |
Reaction Steps
4-Methoxy-1-(2-methoxy-4-nitrophenyl)-1H-imidazole (0.62 g, 2.49 mmol) was dissolved in EtOH (20 mL). Palladium on carbon (10%, 0.106 g, 0.10 mmol) was added. The mixture was shaken for 2 hours under an atmosphere of hydrogen (g). The mixture was filtered, the filter was washed with warm EtOH. The filtrate was concentrated to give the title compound as an oil, 0.52 g (95%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09439904B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-7e1ffaefaab042fabfeff8bf0af068df |
| Source note | uspto-grants-2016_09 |