HCID 66747907, compound → HCID 66746773, compound

Participants

Reaction Steps

3-(3-Chlorophenyl)-2-(3-hydroxyphenyl)acrylonitrile (3.6 g, 14.08 mmol) was dissolved in 100 ml methanol, containing 0.02 eq Pd/C (0.3 g, 0.28 mmol) 10% on C. Hydrogenation was performed at room temperature over night. Reaction was filtered through celite and the solvent evaporated. The residue was suspended in ethyl acetate and the white precipitate was filtered and dried m=3.0 g (94%).

Provenance & Evidence