di-tert-butyl (5R)-2-[4-(benzyloxy)benzyl]-2-(benzyloxycarbonyl)-5-[(tert-butoxycarbonyl)amino]hexanedioate → HCID 70941355, compound

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Reaction Steps

To a solution of 370 mg di-tert-butyl (5R)-2-[4-(benzyloxy)benzyl]-2-(benzyloxycarbonyl)-5-[(tert-butoxycarbonyl)amino]hexanedioate (0.53 mmol) in methanol (10 mL) was added a 10% palladium on carbon hydrogenation catalyst (50 mg) at room temperature. The suspension was stirred for 2.5 hours at room temperature under an atmosphere of hydrogen. The catalyst was removed by filtration and all volatiles were removed in vacuo. The crude product (273 mg, 99% yield) was used in the next step without further purification.

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