反应详情

To a solution of 316 mg (0.59 mmol) di-tert-butyl (4S)—N-(tert-butoxycarbonyl)-4-{(E)-3-[4-(3-hydroxypropyl)phenyl]prop-2-en-1-yl}-L-glutamate in 29 mL of methanol, palladium (10% on charcoal, 126 mg) was added and the suspension was stirred overnight at room temperature under a hydrogen atmosphere. The mixture was filtered over celite, and the solvent was evaporated. The remaining material was used without purification.

1. filtrationThe mixture was filtered over celite
2. customthe solvent was evaporated
3. customThe remaining material was used without purification