HCID 131734510, compound → HCID 123585374, compound

Participants

Reaction Steps

To a solution of 140 mg (0.23 mmol) di-tert-butyl (4R)—N-(tert-butoxycarbonyl)-4-({5-[(E)-3-{[tert-butyl(dimethyl)silyl]oxy}prop-1-en-1-yl]pyridin-2-yl}methyl)-L-glutamate in 8 ml of methanol, palladium (10% on charcoal, 7 mg) was added and the suspension was stirred for 3 h at room temperature under a hydrogen atmosphere. The mixture was filtered over celite, and the solvent was evaporated. The crude material was used without further purification.

Provenance & Evidence