Tetrahydrofuran → HCID 70977299, compound

Participants

Reaction Steps

Dimethyl (2S)-2-amino-5-[4-(fluoromethoxy)benzyl]hexanedioate (37 mg, 113 μmol) was solved in 2 ml of a mixture of tetrahydrofurane and water (2:1), and to the solution, four drops of 1N sodium hydroxide were added. The mixture was stirred at room temperature for 14 h and then concentrated in vacuo. The residue was purified by preparative HPLC and the according fractions were lyophilized to yield 2 mg (4.3%) of the title compound.

Provenance & Evidence