2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → HCID 89768053, compound

Participants

Reaction Conditions

Reaction Steps

To a mixture of methyl((3S)-6-((2,4-dichlorobenzyl)oxy)-2,3-dihydro-1-benzofuran-3-yl)acetate (367 mg) in toluene (5.0 mL) was added DDQ (272 mg). The mixture was stirred at 80° C. for 17 h. After cooling, the insoluble material was removed by filtration and the filtrate was concentrated in vacuo. The residue was purified by silica gel column chromatography (EtOAc/hexane) to give the title compound (263.6 mg).

Provenance & Evidence