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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 591877Generated: October 25, 2026

Sodium Hydroxide → (R)-4-((3R,5R,8S,9S,10R,13R,14S,17R,Z)-6-ethylidene-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

https://huagongshe.com/reaction/591877

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantCID 86706182HCID 86706182—
Product(R)-4-((3R,5R,8S,9S,10R,13R,14S,17R,Z)-6-ethylidene-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acidHCID 86706181—

Reaction Steps

reacting E/Z-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid methyl ester (4A) with NaOH to form E/Z-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid (5A),

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09238673B2
Source datasetuspto-grants-2016_01
ORD IDord-dd914d1a76b34af5b47ae3b9a98e2edf
Source noteuspto-grants-2016_01