HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-(Chloromethyl)benzoselenazolinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-(Hydroxymethyl)benzoselenazolinone | HCID 86747228 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 3-(Chloromethyl)benzoselenazolinone | HCID 86747229 | — |
Reaction Steps
0.55 cm3 of thionyl chloride (0.02 mol) is added dropwise and with stirring into a round-bottom flask containing 0.01 mol of 3-(hydroxymethyl)benzoselenazolinone dissolved in 100 cm3 of chloroform. The mixture is brought to reflux for 2 hours and the chloroform is then evaporated off under reduced pressure. The product is recrystallized in cyclohexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05246951 |
| Source dataset | uspto-grants-1993_09 |
| ORD ID | ord-7bbf869560ef405cb4745a650ec1ed60 |
| Source note | uspto-grants-1993_09 |