Ammonium Acetate → HCID 178514005, compound

Participants

Reaction Steps

In a similar fashion compound to CXXV, (1S,2S,3R,4R)-3-(2,3-Diamino-5-chloro-pyridin-4-ylamino)-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid amide (50.00 mg, 0.1702 mmol), 2-Morpholin-4-yl-pyridine-4-carbaldehyde (36.0 mg, 0.187 mmol) and Ammonium acetate (26.2 mg, 0.340 mmol) were reacted to yield 36.32 mg (46%) of the title compound. (300 MHz, DMSO-d6) 12.35 (s, 1H), 8.26 (s, 1H), 7.79 (s, 1H), 7.52 (s, 1H), 7.38 (s, 2H), 7.25 (s, 1H), 6.39 (s, 2H), 5.15 (s, 1H), 3.75 (s, 4H), 3.54 (s, 4H), 2.90 (s, 1H), 2.80 (s, 1H), 2.62 (s, 1H), 2.26 (s, 1H), 1.38 (s, 1H). MS=466 (M+H), HPLC: 1.76 min. (G Method)

Provenance & Evidence