HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 66661229, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 86646747 | HCID 86646747 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 66661229 | HCID 66661229 | 106.4% |
Reaction Steps
To a solution of tert-butyl {(1R)-1-[1-oxido-6-(trifluoromethyl)-3-pyridinyl]ethyl}carbamate (140 mg, 0.457 mmol) in dioxane (2 mL) was added hydrogen chloride (4.0 M in dioxane; 0.343 mL, 1.371 mmol). The reaction mixture was stirred for 4 h. The reaction mixture was concentrated to dryness to give the hydrochloride salt of the title compound (118 mg). MS 207.1 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09238647B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-f5e3fb45d30b48d18140e45325098c7e |
| Source note | uspto-grants-2016_01 |