HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → Methyl 4-(isocyanatocarbonyl)-2-methoxybenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | Methyl 4-carbamoyl-2-methoxybenzoate | HCID 90019463 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | Methyl 4-(isocyanatocarbonyl)-2-methoxybenzoate | HCID 90019300 | 63.6% |
Reaction Steps
The title compound was prepared according to the procedure described in step-2 of Intermediate-8 by using methyl 4-carbamoyl-2-methoxybenzoate (1.4 g, 6.69 mmol), oxalyl chloride (0.72 mL, 8.03 mmol) and EDC (10 mL) to afford 1.00 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09439890B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-dfe4acc816ba4c0184b7bad8759704d6 |
| Source note | uspto-grants-2016_09 |