HCID 131734559, compound → HCID 22872766, compound

Participants

Reaction Conditions

Reaction Steps

A warmed (50° C.) stirred suspension of magnesium bis-lysinate monohydrate (1.00 g, 3.0 mmol) in methanol (5 mL) under nitrogen was treated with a solution of EPA (0.94 g, 3.1 mmol) in methanol (10 mL) containing alpha-D-tocopherol (100 mg) dissolved in ethyl acetate (0.5 mL), and stirred for 20 min, then most of the methanol was removed in vacuo and replaced with acetonitrile (20 mL). The mixture was stirred for 3 h, filtered, washed with acetonitrile, collected and dried in vacuo to afford 1.855 g (100%) of subject material as a pale beige solid.

Provenance & Evidence