Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | 2-Fluoro-4-(2-methoxyphenyl)pyridine | HCID 68287723 | — |
| Solvent | Acetonitrile--water (1/1) | HCID 18373917 | — |
| Product | HCID 60196540 | HCID 60196540 | — |
Reaction Steps
A mixture of A3 (80 mg, 0.39 mmol) and aniline (102 mg, 1.1 mmol) was heated for 20 minutes at 150° C. in a microwave oven. The title compound B1 was obtained from the residue by preparative HPLC (water/ACN gradient) as an amorphous solid (20 mg, 19%). MS (ES) C18H16N2O requires: 276. found: 277 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09242937B2 |
|---|
| Source dataset | uspto-grants-2016_01 |
|---|
| ORD ID | ord-40ef953193f54e06bc7b1c894f804914 |
|---|
| Source note | uspto-grants-2016_01 |
|---|
