HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-5-(trifluoromethyl)pyridine → 6-chloro-2-(5-trifluoromethyl-pyridin-3-yl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-5-(trifluoromethyl)pyridine | HCID 11127991 | — |
| Reactant | 1-Boc-6-chloroindole-2-boronic acid | HCID 44119151 | — |
| Product | 6-chloro-2-(5-trifluoromethyl-pyridin-3-yl)-1H-indole | HCID 58215685 | — |
Reaction Steps
3-Trifluoromethyl-5-bromopyridine and N-Boc-6-chloro-indole-2-boronic acid are processed according to the procedure described in Example 91 to give 6-chloro-2-(5-trifluoromethyl-pyridin-3-yl)-1H-indole. (ESI) m/z 297.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242963B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-943030eb6f6244d098e824fddaa9a091 |
| Source note | uspto-grants-2016_01 |