HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Boc-6-chloroindole-2-boronic acid → 6-chloro-2-[5-(4-methyl-piperazin-1-ylmethyl)-pyridin-3-yl]-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Boc-6-chloroindole-2-boronic acid | HCID 44119151 | — |
| Reactant | 1-((5-Bromopyridin-3-yl)methyl)-4-methylpiperazine | HCID 58215703 | — |
| Product | 6-chloro-2-[5-(4-methyl-piperazin-1-ylmethyl)-pyridin-3-yl]-1H-indole | HCID 58215813 | — |
Reaction Steps
1-(5-Bromo-pyridin-3-ylmethyl)-4-methyl-piperazine and 6-chloro-1-Boc-indole-2-boronic acid are processed according to the method described in Example 91 to give 6-chloro-2-[5-(4-methyl-piperazin-1-ylmethyl)-pyridin-3-yl]-1H-indole. (ESI) m/z 341.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242963B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-38f4de48a1314ca6a99a4f9a06c7efbc |
| Source note | uspto-grants-2016_01 |