HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-((5-Bromopyridin-3-yl)methyl)isoindoline-1,3-dione → 2-[5-(6-chloro-1-methyl-1H-indol-2-yl)-pyridin-3-ylmethyl]isoindole-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-((5-Bromopyridin-3-yl)methyl)isoindoline-1,3-dione | HCID 22992261 | — |
| Reactant | 6-Chloro-1-methyl-1H-indole-2-boronic acid | HCID 44119594 | — |
| Product | 2-[5-(6-chloro-1-methyl-1H-indol-2-yl)-pyridin-3-ylmethyl]isoindole-1,3-dione | HCID 58215539 | — |
Reaction Steps
6-Chloro-1-methyl-indole-2-boronic acid and 2-(5-bromo-pyridin-3-ylmethyl)-isoindole-1,3-dione are processed according to the method described in Example 100 to give 2-[5-(6-chloro-1-methyl-1H-indol-2-yl)-pyridin-3-ylmethyl]-isoindole-1,3-dione. MS (ESI) m/z 402.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242963B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-03c745afc7a24b829efe8f74bd46587f |
| Source note | uspto-grants-2016_01 |