HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 5-((2,2,2-Trifluoroacetamido)methyl)-2-chloro-4-methoxybenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 2,2,2-Trifluoro-N-(hydroxymethyl)acetamide | HCID 3084931 | — |
| Reactant | 2-Chloro-4-methoxybenzoic acid | HCID 12648026 | — |
| Product | 5-((2,2,2-Trifluoroacetamido)methyl)-2-chloro-4-methoxybenzoic acid | HCID 90019421 | 39.9% |
Reaction Steps
The title compound was prepared according to the procedure described in step-1 of Intermediate-26 by using 2-chloro-4-methoxybenzoic acid (0.060 g), 2,2,2-trifluoro-N-(hydroxymethyl)acetamide (0.050 g) and H2SO4 (2 mL) to afford 0.040 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09439890B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-28def1e1d84f42db8ac98d0a93fae888 |
| Source note | uspto-grants-2016_09 |