HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous chloride dihydrate → N-(4-chloro-3-hydrazinylbenzyl)-2,2-dimethylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Reactant | N-(3-amino-4-chlorobenzyl)pivalamide | HCID 66765386 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | N-(4-chloro-3-hydrazinylbenzyl)-2,2-dimethylpropanamide | HCID 90019617 | 65,169.398% |
Reaction Steps
The title compound was prepared according to the procedure described in step-1 of Intermediate-61 by using N-(3-amino-4-chlorobenzyl)pivalamide (1.80 g), NaNO2 (0.62 g, 0.009 mmol), SnCl2.2H2O (4.2 g, 0.018 mmol) and conc. HCl (30 mL) to afford 1.5 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09439890B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-55d69b52e9534e55b7cbce9b803cc3e3 |
| Source note | uspto-grants-2016_09 |