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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 59403Generated: October 25, 2026

Oxalyl chloride → 3-Fluoro-4-(trifluoromethyl)benzoyl isocyanate

https://huagongshe.com/reaction/59403

Reaction equation

Participants

RoleNameHCIDCharge
ReactantOxalyl chlorideHCID 65578—
Reactant3-Fluoro-4-(trifluoromethyl)benzamideHCID 2737543—
Solvent1,2-DichloroethaneHCID 11—
Product3-Fluoro-4-(trifluoromethyl)benzoyl isocyanateHCID 90019862—

Reaction Steps

The title compound was prepared according to the procedure described in step-2 of Intermediate-8 by using 3-fluoro-4-(trifluoromethyl)benzamide (0.200 g), oxalyl chloride (0.025 mL) and EDC (15 mL) to afford 0.150 g of the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09439890B2
Source datasetuspto-grants-2016_09
ORD IDord-d06a62af6f2c4e188397f9c031e4e59d
Source noteuspto-grants-2016_09