HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 3-Fluoro-4-iodobenzoyl isocyanate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 3-Fluoro-4-iodobenzamide | HCID 53583829 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | 3-Fluoro-4-iodobenzoyl isocyanate | HCID 90019121 | — |
Reaction Steps
The title compound was prepared according to the procedure described in step-2 of Intermediate-8 by using 3-fluoro-4-iodobenzamide (2.0 g), oxalyl chloride (0.120 mL) and EDC (25 mL) to afford 1.0 g of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09439890B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-d65519cd3548476d8209cadf129712db |
| Source note | uspto-grants-2016_09 |