HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Ethyl-6-methylpyridin-2-amine → 4-((3,5-dimethylisoxazol-4-yl)-methoxy)-N-(3-ethyl-6-methylpyridin-2-yl)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Ethyl-6-methylpyridin-2-amine | HCID 3016311 | — |
| Reactant | 4-((3,5-Dimethylisoxazol-4-yl)methoxy)benzene-1-sulfonyl chloride | HCID 16490702 | — |
| Product | 4-((3,5-dimethylisoxazol-4-yl)-methoxy)-N-(3-ethyl-6-methylpyridin-2-yl)benzenesulfonamide | HCID 89876047 | 58.2% |
Reaction Steps
The title compound (70.1 mg) was prepared from 3-ethyl-6-methylpyridin-2-amine (0.091 g, 0.3 mmol) and 4-((3,5-dimethylisoxazol-4-yl)methoxy)benzene-1-sulfonyl chloride (0.136 g, 0.45 mmol), following the procedure described for Intermediate 54. LCMS (2 min, formic) Rt 1.02 min, m/z (ES+) 402 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242972B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-ddbb762fe560468cb24f203d5f37aa08 |
| Source note | uspto-grants-2016_01 |