HCID 89876084, compound → HCID 72194937, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 2-(4-(1-hydroxy-2-morpholinoethyl)-N-isobutylphenylsulfonamido)-5-isopropylpyridine 1-oxide (130 mg, 0.272 mmol) in ethanol (1 mL) at 20° C. was added molybdenum hexacarbonyl (71.9 mg, 0.272 mmol). The reaction vessel was sealed and heated by microwaves to 150° C. for 1 hour. After cooling, the reaction was filtered and evaporated in vacuo to give the crude product. The crude was purified by mass directed autoprep (ammonium carbonate modifier) but gave impure product. The sample was repurified by mass directed autoprep (formic acid modifier) to give the title product, 34.1 mg. LCMS (2 min, formic) Rt 0.85 min, m/z (ES+) 462 (M+H).

Provenance & Evidence