HCID 89875888, compound → HCID 72194938, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 2-(4-(1-hydroxy-2-((3-methyloxetan-3-yl)amino)ethyl)-N-isobutylphenylsulfonamido)-5-isopropylpyridine 1-oxide (71.9 mg, 0.151 mmol), in ethanol (1 mL) stirred in air at 20° C., was added molybdenum hexacarbonyl (39.7 mg, 0.151 mmol). The reaction was heated by microwaves to 100° C. for 10 minutes. After cooling, the reaction mixture was filtered and solids washed with ethanol (5 mL) and dichloromethane (5 mL). The combined filtrate was evaporated in vacuo and the crude sample purified by mass directed autoprep (ammonium carbonate modifier). The relevant fractions were concentrated under a stream of nitrogen to give the title product, 7.5 mg. LCMS (2 min, formic) Rt 0.91 min, m/z (ES+) 462 (M+H).

Provenance & Evidence