HCID 21660613, compound → HCID 10821508, compound

Participants

Reaction Steps

A solution of (6-(thiazol-2-yl)pyridin-2-yl)methanol (171 mg; 0.89 mmol) in anh. DCM (6 ml) was treated with MnO2 (1.164 g; 13.38 mmol), and the resulting mixture was stirred at rt, under nitrogen, for 2 h. The resulting reaction mixture was then filtered over celite, and the separated solids were washed with DCM. The filtrate was concentrated to dryness under reduced pressure giving 6-(thiazol-2-yl)picolinaldehyde as a yellow solid. LC-MS (conditions A): tR=0.62 min.; [M+H]+: 191.08 g/mol.

Provenance & Evidence