HCID 9877565, compound → [2,2'-Bipyridine]-4-carbaldehyde

Participants

Reaction Steps

A solution of [2,2′-bipyridin]-4-ylmethanol (120 mg; 0.64 mmol) in anh. THF (5 ml) was treated with MnO2 (873 mg; 10.05 mmol), and the resulting mixture was stirred at rt, under nitrogen, for 6.5 h. The resulting reaction mixture was then filtered over celite, and the separated solids were washed with THF. The filtrate was concentrated to dryness under reduced pressure giving [2,2′-bipyridine]-4-carbaldehyde as a colorless solid. LC-MS (conditions A): tR=0.30 min.; [M+H]+: 185.17 g/mol.

Provenance & Evidence