HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-ethoxy-2-iodo- → HCID 69082481, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-ethoxy-2-iodo- | HCID 136415 | — |
| Reactant | 5-(2,6-Dimethoxyphenyl)pyrrolidin-2-one | HCID 69080911 | — |
| Reactant | Methyl 4-amino-4-(2,6-dimethoxyphenyl)butanoate | HCID 69082397 | — |
| Reactant | Methyl 4-((tert-butylsulfinyl)imino)butanoate | HCID 86695623 | — |
| Product | HCID 69082481 | HCID 69082481 | — |
Reaction Steps
Synthesized from methyl 4-((tert-butylsulfinyl)imino)butanoate and commercially available 1-ethoxy-2-iodobenzene according to the procedures described for the preparations of methyl 4-amino-4-(2,6-dimethoxyphenyl)butanoate and 5-(2,6-dimethoxyphenyl)pyrrolidin-2-one. The target product 5-(2-ethoxyphenyl)pyrrolidin-2-one was obtained as a colorless solid after purification by FC (heptane/AcOEt=7/3 to 3/7). LC-MS (conditions D): tR=0.81 min.; [M+H]+: 205.99 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-38ce28f7d58443a1b399ce79b538f257 |
| Source note | uspto-grants-2016_01 |