Water → N-(dibenzo[b,d]furan-2-ylmethyl)-2-methylpropane-2-sulfinamide

Participants

Reaction Steps

A solution of N-(dibenzo[b,d]furan-2-ylmethylene)-2-methylpropane-2-sulfinamide (2.260 g; 7.55 mmol) in anh. MeOH (27 ml) and anh. DCM (57 ml) was treated with NaBH4 (343 mg; 9.06 mmol), and the resulting mixture was stirred at rt, under nitrogen, for 10 min. Water and DCM were added, and the organic layer was then dried over anh. MgSO4, filtered, and concentrated to dryness under reduced pressure affording N-(dibenzo[b,d]furan-2-ylmethyl)-2-methylpropane-2-sulfinamide as a yellow solid. LC-MS (conditions A): tR=0.82 min.; [M+H]+: 302.01 g/mol.

Provenance & Evidence