Zurück
HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 594434Erstellt: 25. Oktober 2026

3-(2-Methyl-1,3-thiazol-4-yl)benzaldehyde → 6-(2,6-Dimethoxyphenyl)-1-(3-(2-methylthiazol-4-yl)benzyl)piperidin-2-one

https://huagongshe.com/reaction/594434

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt3-(2-Methyl-1,3-thiazol-4-yl)benzaldehydeHCID 7127782—
EduktMethyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoateHCID 69082713—
Produkt6-(2,6-Dimethoxyphenyl)-1-(3-(2-methylthiazol-4-yl)benzyl)piperidin-2-oneHCID 69082516—

Reaktionsschritte

Prepared according to the described general procedure 1 (GP1) by reaction of methyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoate with commercially available 3-(2-methylthiazol-4-yl)benzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.85 min.; [M+H]+: 423.01 g/mol.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS09242970B2
Quelldatensatzuspto-grants-2016_01
ORD IDord-3c18e513e5684266b69d2f80f415b84d
Quellennotizuspto-grants-2016_01