Methyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoate → HCID 69082500, compound

HRID 594464Notes

Reaction equation

HRID 594464 reaction equation
[NH2:1][CH:2]([C:10]1[C:15]([O:16][CH3:17])=[CH:14][CH:13]=[CH:12][C:11]=1[O:18][CH3:19])[CH2:3][CH2:4][CH2:5][C:6]([O:8]C)=O.[N:20]1([C:25]2[CH:26]=[C:27]([CH:30]=[CH:31][CH:32]=2)[CH:28]=O)[CH:24]=[CH:23][N:22]=[N:21]1>>[N:20]1([C:25]2[CH:26]=[C:27]([CH:30]=[CH:31][CH:32]=2)[CH2:28][N:1]2[CH:2]([C:10]3[C:15]([O:16][CH3:17])=[CH:14][CH:13]=[CH:12][C:11]=3[O:18][CH3:19])[CH2:3][CH2:4][CH2:5][C:6]2=[O:8])[CH:24]=[CH:23][N:22]=[N:21]1

Participants

3

Reactant 2

HCID 69082713Methyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoateHCID 834815293-(1H-1,2,3-triazol-1-yl)benzaldehyde

Product 1

HCID 69082500HCID 69082500, compound

Procedure

Prepared according to the described general procedure 1 (GP1) by reaction of methyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoate with 3-(1H-1,2,3-triazol-1-yl)benzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.71 min.; [M+H]+: 393.08 g/mol.

Workup

  1. customPrepared
  2. customSubsequent purification by preparative HPLC
  3. customafforded the target compound

Sources & evidence

ORD record
ord-18336ac59c404223b5f34e20f3a693cf
Source dataset
uspto-grants-2016_01
Patent number
US09242970B2

Reaction notes

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