3-(2-Methyl-1,3-thiazol-4-yl)benzaldehyde → 6-(2,4-Dimethoxypyridin-3-yl)-1-(3-(2-methylthiazol-4-yl)benzyl)piperidin-2-one

Participants

Reaction Steps

Prepared according to the described general procedure 1 (GP1) by reaction of methyl 5-amino-5-(2,4-dimethoxypyridin-3-yl)pentanoate with commercially available 3-(2-methylthiazol-4-yl)benzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.71 min.; [M+H]+: 423.95 g/mol.

Provenance & Evidence