HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dibenzo(b,d)furan-2-carboxaldehyde → 1-(Dibenzo[b,d]furan-2-ylmethyl)-6-(2,4-dimethoxypyridin-3-yl)piperidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dibenzo(b,d)furan-2-carboxaldehyde | HCID 220843 | — |
| Reactant | Methyl 5-amino-5-(2,4-dimethoxypyridin-3-yl)pentanoate | HCID 69082421 | — |
| Product | 1-(Dibenzo[b,d]furan-2-ylmethyl)-6-(2,4-dimethoxypyridin-3-yl)piperidin-2-one | HCID 69085151 | — |
Reaction Steps
Prepared according to the described general procedure 1 (GP1) by reaction of methyl 5-amino-5-(2,4-dimethoxypyridin-3-yl)pentanoate with commercially available dibenzo[b,d]furan-2-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.83 min.; [M+H]+: 416.86 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-9f7b7ce1ff8a4b7cb114139cd589d153 |
| Source note | uspto-grants-2016_01 |