HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6-(1H-Pyrazol-1-yl)-2-pyridinecarboxaldehyde → 1-((6-(1H-pyrazol-1-yl)pyridin-2-yl)methyl)-6-(3,5-dimethoxypyridin-4-yl)piperidin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 6-(1H-Pyrazol-1-yl)-2-pyridinecarboxaldehyde | HCID 10511407 | — |
| Edukt | Methyl 5-amino-5-(3,5-dimethoxypyridin-4-yl)pentanoate | HCID 69082669 | — |
| Produkt | 1-((6-(1H-pyrazol-1-yl)pyridin-2-yl)methyl)-6-(3,5-dimethoxypyridin-4-yl)piperidin-2-one | HCID 69080959 | — |
Reaktionsschritte
Prepared according to the described general procedure 1 (GP1) by reaction of methyl 5-amino-5-(3,5-dimethoxypyridin-4-yl)pentanoate with 6-(1H-pyrazol-1-yl)picolinaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.49 min.; [M+H]+: 393.79 g/mol.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09242970B2 |
| Quelldatensatz | uspto-grants-2016_01 |
| ORD ID | ord-4d109b9508a345fab2c75fae0e89054d |
| Quellennotiz | uspto-grants-2016_01 |