HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Phenylpyridine-3-carbaldehyde → 7-(2,6-Dimethoxyphenyl)-1-((5-phenylpyridin-3-yl)methyl)azepan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Phenylpyridine-3-carbaldehyde | HCID 15519764 | — |
| Reactant | Methyl 6-amino-6-(2,6-dimethoxyphenyl)hexanoate | HCID 69082587 | — |
| Product | 7-(2,6-Dimethoxyphenyl)-1-((5-phenylpyridin-3-yl)methyl)azepan-2-one | HCID 69085753 | — |
Reaction Steps
Prepared according to the described general procedure 1 (GP1) by reaction of methyl 6-amino-6-(2,6-dimethoxyphenyl)hexanoate with 5-phenylnicotinaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions I): tR=1.26 min.; [M+H]+: 417.20 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-0b2c254534f644e8994edc892aaa94da |
| Source note | uspto-grants-2016_01 |