HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenyl-1H-pyrazole-4-carbaldehyde → 7-(2,6-dimethoxyphenyl)-1-((1-phenyl-1H-pyrazol-4-yl)methyl)azepan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenyl-1H-pyrazole-4-carbaldehyde | HCID 952089 | — |
| Reactant | Methyl 6-amino-6-(2,6-dimethoxyphenyl)hexanoate | HCID 69082587 | — |
| Product | 7-(2,6-dimethoxyphenyl)-1-((1-phenyl-1H-pyrazol-4-yl)methyl)azepan-2-one | HCID 69082718 | — |
Reaction Steps
Prepared according to the described general procedure 1 (GP1) by reaction of methyl 6-amino-6-(2,6-dimethoxyphenyl)hexanoate with commercially available 1-phenyl-1H-pyrazole-4-carbaldehyde. Subsequent purification by preparative HPLC the target compound. LC-MS (conditions I): tR=1.27 min.; [M+H]+: 405.81 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-3dde72294fd24360bb8c5291efa88a97 |
| Source note | uspto-grants-2016_01 |