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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 594514Generated: October 31, 2026

3-(pyridin-4-yl)benzaldehyde → 7-(2,6-Dimethoxyphenyl)-1-(3-(pyridin-4-yl)benzyl)azepan-2-one

https://huagongshe.com/reaction/594514

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(pyridin-4-yl)benzaldehydeHCID 2795563—
ReactantMethyl 6-amino-6-(2,6-dimethoxyphenyl)hexanoateHCID 69082587—
Product7-(2,6-Dimethoxyphenyl)-1-(3-(pyridin-4-yl)benzyl)azepan-2-oneHCID 69083698—

Reaction Steps

Prepared according to the described general procedure 1 (GP1) by reaction of methyl 6-amino-6-(2,6-dimethoxyphenyl)hexanoate with commercially available 3-(pyridin-4-yl)benzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.65 min.; [M+H]+: 417.01 g/mol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09242970B2
Source datasetuspto-grants-2016_01
ORD IDord-65ea4b0a8fe64d4393940e29c96a75a3
Source noteuspto-grants-2016_01