HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-1,3-benzothiazole-6-carbaldehyde → 7-(2,6-Dimethoxyphenyl)-1-((2-methylbenzo[d]thiazol-6-yl)methyl)azepan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-1,3-benzothiazole-6-carbaldehyde | HCID 4285597 | — |
| Reactant | Methyl 6-amino-6-(2,6-dimethoxyphenyl)hexanoate | HCID 69082587 | — |
| Product | 7-(2,6-Dimethoxyphenyl)-1-((2-methylbenzo[d]thiazol-6-yl)methyl)azepan-2-one | HCID 86695643 | — |
Reaction Steps
Prepared according to the described general procedure 1 (GP1) by reaction of methyl 6-amino-6-(2,6-dimethoxyphenyl)hexanoate with 2-methylbenzo[d]thiazole-6-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.83 min.; [M+H]+: 411.03 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-9bcc45da48bd4aa592bd677defc16e8c |
| Source note | uspto-grants-2016_01 |