Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Quinolinecarboxaldehyde → 5-(2,6-Dimethoxyphenyl)-1-(quinolin-2-ylmethyl)pyrrolidin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Quinolinecarboxaldehyde | HCID 79619 | — |
| 반응물 | Methyl 4-amino-4-(2,6-dimethoxyphenyl)butanoate | HCID 69082397 | — |
| 생성물 | 5-(2,6-Dimethoxyphenyl)-1-(quinolin-2-ylmethyl)pyrrolidin-2-one | HCID 69085133 | — |
반응 단계
Prepared according to the described general procedure 1 (GP1) by reaction of methyl 4-amino-4-(2,6-dimethoxyphenyl)butanoate with commercially available quinoline-2-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.57 min.; [M+H]+: 363.36 g/mol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09242970B2 |
| 출처 데이터셋 | uspto-grants-2016_01 |
| ORD ID | ord-b2fffa44debe4558b147972100ca3a95 |
| 출처 메모 | uspto-grants-2016_01 |