Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Phenylbenzaldehyde → 1-([1,1'-Biphenyl]-3-ylmethyl)-5-(2,6-dimethoxyphenyl)pyrrolidin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Phenylbenzaldehyde | HCID 121053 | — |
| 반응물 | Methyl 4-amino-4-(2,6-dimethoxyphenyl)butanoate | HCID 69082397 | — |
| 생성물 | 1-([1,1'-Biphenyl]-3-ylmethyl)-5-(2,6-dimethoxyphenyl)pyrrolidin-2-one | HCID 69085765 | — |
반응 단계
Prepared according to the described general procedure 2 (GP2) by reaction of methyl 4-amino-4-(2,6-dimethoxyphenyl)butanoate with commercially available [1,1′-biphenyl]-3-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.91 min.; [M+H]+: 388.11 g/mol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09242970B2 |
| 출처 데이터셋 | uspto-grants-2016_01 |
| ORD ID | ord-63de9447d99641cbaecf12deef2cf682 |
| 출처 메모 | uspto-grants-2016_01 |