HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Phenylpyridine-2-carbaldehyde → 5-(2,6-Dimethoxyphenyl)-1-((6-phenylpyridin-2-yl)methyl)pyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Phenylpyridine-2-carbaldehyde | HCID 13522416 | — |
| Reactant | Methyl 4-amino-4-(2,6-dimethoxyphenyl)butanoate | HCID 69082397 | — |
| Product | 5-(2,6-Dimethoxyphenyl)-1-((6-phenylpyridin-2-yl)methyl)pyrrolidin-2-one | HCID 69083522 | — |
Reaction Steps
Prepared according to the described general procedure 2 (GP2) by reaction of methyl 4-amino-4-(2,6-dimethoxyphenyl)butanoate with 6-phenylpicolinaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.76 min.; [M+H]+: 389.14 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-8ddf9ff8b2f9432282f34b8500ac8375 |
| Source note | uspto-grants-2016_01 |