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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 594578Generated: November 3, 2026

4-(Bromomethyl)-2-fluoro-1-(trifluoromethoxy)benzene → HCID 69085702, compound

https://huagongshe.com/reaction/594578

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Bromomethyl)-2-fluoro-1-(trifluoromethoxy)benzeneHCID 17750672—
Reactant6-(2,6-Dimethoxyphenyl)piperidin-2-oneHCID 69082526—
ProductHCID 69085702HCID 69085702—

Reaction Steps

Prepared according to the described general procedure 4 (GP4) by reaction of 6-(2,6-dimethoxyphenyl)piperidin-2-one with commercially available 4-(bromomethyl)-2-fluoro-1-(trifluoromethoxy)benzene. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions E): tR=0.81 min.; [M+H]+: 428.21 g/mol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09242970B2
Source datasetuspto-grants-2016_01
ORD IDord-5e356593bc5642ba8230f91fcd6ce234
Source noteuspto-grants-2016_01