Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 594584Generated: October 30, 2026

1,3-Benzodioxole, 5-(chloromethyl)- → HCID 69084951, compound

https://huagongshe.com/reaction/594584

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Benzodioxole, 5-(chloromethyl)-HCID 88713—
Reactant6-(2,6-Dimethoxyphenyl)piperidin-2-oneHCID 69082526—
ProductHCID 69084951HCID 69084951—

Reaction Steps

Prepared according to the described general procedure 4 (GP4) by reaction of 6-(2,6-dimethoxyphenyl)piperidin-2-one with commercially available 5-(chloromethyl)benzo[d][1,3]dioxole. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions E): tR=0.71 min.; [M+H]+: 369.68 g/mol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09242970B2
Source datasetuspto-grants-2016_01
ORD IDord-5a330b17fe4a425e87eb12986e4fd1b7
Source noteuspto-grants-2016_01