HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(Bromomethyl)-2,1,3-benzoxadiazole → 1-(Benzo[c][1,2,5]oxadiazol-5-ylmethyl)-6-(2,6-dimethoxyphenyl)piperidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(Bromomethyl)-2,1,3-benzoxadiazole | HCID 2735587 | — |
| Reactant | 6-(2,6-Dimethoxyphenyl)piperidin-2-one | HCID 69082526 | — |
| Product | 1-(Benzo[c][1,2,5]oxadiazol-5-ylmethyl)-6-(2,6-dimethoxyphenyl)piperidin-2-one | HCID 69083827 | — |
Reaction Steps
Prepared according to the described general procedure 4 (GP4) by reaction of 6-(2,6-dimethoxyphenyl)piperidin-2-one with commercially available 5-(bromomethyl)benzo[c][1,2,5]oxadiazole. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions E): tR=0.74 min.; [M+H]+: 368.1 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-3d26f533278a4f6f9d507e664bb60065 |
| Source note | uspto-grants-2016_01 |