HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Bromomethyl)benzo[b]thiophene → 1-(Benzo[b]thiophen-2-ylmethyl)-6-(2,6-dimethoxyphenyl)piperidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Bromomethyl)benzo[b]thiophene | HCID 13642605 | — |
| Reactant | 6-(2,6-Dimethoxyphenyl)piperidin-2-one | HCID 69082526 | — |
| Product | 1-(Benzo[b]thiophen-2-ylmethyl)-6-(2,6-dimethoxyphenyl)piperidin-2-one | HCID 69082281 | — |
Reaction Steps
Prepared according to the described general procedure 4 (GP4) by reaction of 6-(2,6-dimethoxyphenyl)piperidin-2-one with 2-(bromomethyl)benzo[b]thiophene. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions F): tR=0.86 min.; [M+H]+: 382.22 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-1e0b1728f4ac4fbcbf805217f32d6b6b |
| Source note | uspto-grants-2016_01 |