HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(bromomethyl)-2,2-difluorobenzo[d][1,3]dioxole → HCID 69083652, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(bromomethyl)-2,2-difluorobenzo[d][1,3]dioxole | HCID 20311383 | — |
| Reactant | 6-(2,6-Dimethoxyphenyl)piperidin-2-one | HCID 69082526 | — |
| Product | HCID 69083652 | HCID 69083652 | — |
Reaction Steps
Prepared according to the described general procedure 4 (GP4) by reaction of 6-(2,6-dimethoxyphenyl)piperidin-2-one with 5-(bromomethyl)-2,2-difluorobenzo[d][1,3]dioxole. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.91 min.; [M+H]+: 406.17 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-60c9e5fdd6cf47589c592441b3057948 |
| Source note | uspto-grants-2016_01 |