HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(Bromomethyl)-2-phenoxypyridine → 6-(2,6-Dimethoxyphenyl)-1-((6-phenoxypyridin-3-yl)methyl)piperidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(Bromomethyl)-2-phenoxypyridine | HCID 69082400 | — |
| Reactant | 6-(2,6-Dimethoxyphenyl)piperidin-2-one | HCID 69082526 | — |
| Product | 6-(2,6-Dimethoxyphenyl)-1-((6-phenoxypyridin-3-yl)methyl)piperidin-2-one | HCID 69082656 | — |
Reaction Steps
Prepared according to the described general procedure 4 (GP4) by reaction of 6-(2,6-dimethoxyphenyl)piperidin-2-one with 5-(bromomethyl)-2-phenoxypyridine. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.84 min.; [M+H]+: 419.25 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-271bc0ae8c3240dbbd1255c8a357060f |
| Source note | uspto-grants-2016_01 |