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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 594633Generated: October 27, 2026

2-Methoxybenzaldehyde → 6-(2-Methoxyphenyl)-1-(naphthalen-2-ylmethyl)piperidin-2-one

https://huagongshe.com/reaction/594633

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethoxybenzaldehydeHCID 8658—
Reactant1-(2-Naphthyl)methanamineHCID 137282—
Product6-(2-Methoxyphenyl)-1-(naphthalen-2-ylmethyl)piperidin-2-oneHCID 69083719—

Reaction Steps

Prepared according to the described general procedure 6 (GP6) with commercially available naphthalen-2-ylmethanamine and commercially available 2-methoxybenzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions H): tR=1.35 min.; [M+H]+: 346.35 g/mol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09242970B2
Source datasetuspto-grants-2016_01
ORD IDord-c4629de8fb0b4ddba7066b267e92a1bb
Source noteuspto-grants-2016_01