2,6-Dimethoxybenzaldehyde → HCID 69082437, compound

HRID 594636Notes

Reaction equation

HRID 594636 reaction equation
[NH:1]1[C:10]2[C:5](=[CH:6][C:7]([CH2:11][NH2:12])=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1.[CH3:13][O:14][C:15]1[CH:22]=[CH:21][CH:20]=[C:19]([O:23][CH3:24])[C:16]=1[CH:17]=O>>[CH3:13][O:14][C:15]1[CH:22]=[CH:21][CH:20]=[C:19]([O:23][CH3:24])[C:16]=1[CH:17]1[N:12]([CH2:11][C:7]2[CH:6]=[C:5]3[C:10](=[CH:9][CH:8]=2)[NH:1][CH2:2][CH2:3][CH2:4]3)[C:15](=[O:14])[CH2:16][CH2:19][CH2:20]1

Participants

3

Reactant 2

HCID 964042,6-DimethoxybenzaldehydeHCID 50989748HCID 50989748, compound

Product 1

HCID 69082437HCID 69082437, compound

Procedure

Prepared according to the described general procedure 6 (GP6) with (1,2,3,4-tetrahydroquinolin-6-yl)methanamine and commercially available 2,6-dimethoxybenzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions E): tR=0.53 min.; [M+H]+: 381.15 g/mol.

Workup

  1. customPrepared
  2. customSubsequent purification by preparative HPLC
  3. customafforded the target compound

Sources & evidence

ORD record
ord-dd2f6992149e414c9fd7440550ed516e
Source dataset
uspto-grants-2016_01
Patent number
US09242970B2

Reaction notes

Loading…