2,6-Dimethoxybenzaldehyde → HCID 69083628, compound

HRID 594643Notes

Reaction equation

HRID 594643 reaction equation
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:3]1[CH2:11][NH2:12].[CH3:13][O:14][C:15]1[CH:22]=[CH:21][CH:20]=[C:19]([O:23][CH3:24])[C:16]=1[CH:17]=O>>[CH3:13][O:14][C:15]1[CH:22]=[CH:21][CH:20]=[C:19]([O:23][CH3:24])[C:16]=1[CH:17]1[N:12]([CH2:11][C:3]2[N:2]([CH3:1])[C:10]3[C:5]([CH:4]=2)=[CH:6][CH:7]=[CH:8][CH:9]=3)[C:15](=[O:14])[CH2:16][CH2:19][CH2:20]1

Participants

3

Reactant 2

HCID 964042,6-DimethoxybenzaldehydeHCID 141969461-(1-Methyl-1H-indol-2-yl)methanamine

Product 1

HCID 69083628HCID 69083628, compound

Procedure

Prepared according to the described general procedure 6 (GP6) with commercially available (1-methyl-1H-indol-2-yl)methanamine and commercially available 2,6-dimethoxybenzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions E): tR=0.78 min.; [M+H]+: 379.31 g/mol.

Workup

  1. customPrepared
  2. customSubsequent purification by preparative HPLC
  3. customafforded the target compound

Sources & evidence

ORD record
ord-91818d0876fd47d79c0f83b9a1a1b4a3
Source dataset
uspto-grants-2016_01
Patent number
US09242970B2

Reaction notes

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