2,6-Dimethoxybenzaldehyde → HCID 69081380, compound

HRID 594645Notes

Reaction equation

HRID 594645 reaction equation
[CH3:1][C:2]1[O:3][C:4]2[CH:10]=[CH:9][C:8]([CH2:11][NH2:12])=[CH:7][C:5]=2[N:6]=1.[CH3:13][O:14][C:15]1[CH:22]=[CH:21][CH:20]=[C:19]([O:23][CH3:24])[C:16]=1[CH:17]=O>>[CH3:13][O:14][C:15]1[CH:22]=[CH:21][CH:20]=[C:19]([O:23][CH3:24])[C:16]=1[CH:17]1[N:12]([CH2:11][C:8]2[CH:9]=[CH:10][C:4]3[O:3][C:2]([CH3:1])=[N:6][C:5]=3[CH:7]=2)[C:4](=[O:3])[CH2:5][CH2:7][CH2:8]1

Participants

3

Reactant 2

HCID 964042,6-DimethoxybenzaldehydeHCID 532566422-Methyl-5-benzoxazolemethanamine

Product 1

HCID 69081380HCID 69081380, compound

Procedure

Prepared according to the described general procedure 6 (GP6) with (2-methylbenzo[d]oxazol-5-yl)methanamine and commercially available 2,6-dimethoxybenzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions E): tR=0.70 min.; [M+H]+: 381.27 g/mol.

Workup

  1. customPrepared
  2. customSubsequent purification by preparative HPLC
  3. customafforded the target compound

Sources & evidence

ORD record
ord-ddaf4145d4e1483aad67b124a3af0258
Source dataset
uspto-grants-2016_01
Patent number
US09242970B2

Reaction notes

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